Clinical and genetic characteristics of adult patients with AML with NUP98 translocations. (A) Ages of adult patients with AML without NUP98 rearrangement (n = 283) compared with those with NUP98 rearrangement (n = 8). (B) Comutations detected in adult patients with AML with NUP98 rearrangement through targeted NGS. The scheme shows the number of mutations per patient, with the corresponding NUP98 fusion partner indicated along the lower x-axis, the patient ID along the upper x-axis, and the comutated gene along the y-axis. The number of mutations per gene are determined by color; 1 detected mutation is represented by light blue and 2 mutations in the same gene by dark blue.