Figure 2.
ECNM. (A) Kaplan-Meier estimates of overall survival (OS) in patients with systemic mastocytosis (SM) with 0 points, 1 to 2 points, vs 3 to 5 points by assignment of 1 point each to serum tryptase ≥125 μg/L, alkaline phosphatase (AP) ≥150 U/L, lactate dehydrogenase (LDH) ≥260 U/L, albumin ≤34 mg/dL, and β2-microglobulin ≥2.5 mg/L; apower =1.000, bpower = 1.000. (B) Kaplan-Meier estimates of OS in patients with SM based on the multivariable model with 0 points, 1.5 points, vs ≥1.5 points by assignment of 1 point to LDH ≥260 U/L, and 1.5 points each to albumin ≤34 mg/dL and β2-microglobulin ≥2.5 mg/L; cpower = 1.000, dpower = 0.998. (C) Kaplan-Meier estimates of OS in patients weighted as International Prognostic Scoring System for Mastocytosis-advanced SM1/2 with 0 points vs ≥1 points. epower = 0.441. The P values refer to the log-rank test.