Figure 4.
GREM. (A) Violin plots on the distribution of the alkaline phosphatase (AP) subtypes in 24 patients with advanced systemic mastocytosis (AdvSM). (B) Pearson and Spearman correlations of the AP levels with other (liver and bone marrow) specific parameters. ∗Significant P values adjusted by Holm-Bonferroni method. (C) Kaplan-Meier estimates of overall survival in patients with AdvSM stratified according to AP levels ≥150 U/L/<150 U/L. apower = 0.974. Alb, albumin; ASAT, aspartate aminotransferase; Bili, bilirubin; MC-I, BM mast cell infiltration; O.lysis, osteolysis; O.poris, osteoporosis.