HMGA2 overexpression in HSC/Ps causes lethal noninfectious pneumonia in MDS mice. (A-B) H&E staining of lung section from indicated mice. Scale bars: top panels, 250 μm (original magnification ×40); middle panels, 50 μm (original magnification ×100); and bottom panels, 25 μm (original magnification ×400). Lung injury score of individual samples is shown in panel B (n = 3 per each group). More than 10 random high-power fields were scored. Data are presented as the mean ± SD. (C-D) Flow cytometric analysis of lung-infiltrated cells of indicated mice (n = 3 per each group). Frequencies of CD11b⁺ myeloid cells and Ly6G⁺ neutrophils within lung-infiltrated cells are shown in panel D. Data are presented as the mean ± SD. ∗∗P < .01.