Cytokine levels are valuable markers for predicting early death in patients with TAM. (A) CIR of early death between patients with TAM with high and low levels of IL-1b (high, n = 64; low, n = 64; CIR, 20.3% [95% CI, 9.8-29.6] vs 1.6% [95% CI, 0.0-4.6]; P < .001); (B) high and low levels of IL-1ra (high, n = 36; low, n = 90; CIR, 30.6% [95% CI, 13.8-44.1] vs 3.4% [95% CI, 0.0-7.0]; P < .001); (C) high and low levels of IL-6 (high, n = 28; low, n = 98; CIR, 32.1% [95% CI, 12.4-47.4] vs 4.1% [95% CI, 0.0-8.0]; P < .001); (D) high and low levels of IL-8 (high, n = 35; low, n = 90; CIR, 31.4% [95% CI, 14.2-45.2] vs 2.2% [95% CI, 0.0-5.3]; P < .001); and (E) high and low levels of IL-13 (high, n = 69; low, n = 59; CIR, 18.8% [95% CI, 9.1-27.6] vs 1.7% [95% CI, 0.0-4.9]; P < .001).