Bronchiectasis throughout treatment with leniolisib. Lung computed tomography scans from (A) P1, (B) P4, and (C) P5 who developed bronchiectasis before entry into the trial (left) and year 6 of treatment with leniolisib (right). L, left; Pos, posterior; R, right. +Images for P1 and P4 were taken ∼1 year before entry into the DFT, and the image for P5 was taken ∼4 years before exposure to leniolisib.