Figure 1.
SOX11 is exclusively expressed in EBV− BL cases. (A-B) SOX11 mRNA expression (log2-transformed values) according to EBV status (EBV− and EBV+) (A) and epidemiological variant (endemic BL and sporadic BL) (B) of 117 pediatric BL cases. Red circle highlights high SOX11 expression in 3 BLs from endemic areas. Wilcoxon text was performed to test differences between groups. (C) Frequency of patients who are SOX11+ and SOX11− (by IHC) in an independent series of pediatric and adult sBLs (n = 189), according to EBV status. The Cochran-Mantel-Haenszel test was performed to test differences between the frequency in EBV− and in EBV+, while adjusting for cohort and group.

SOX11 is exclusively expressed in EBV− BL cases. (A-B) SOX11 mRNA expression (log2-transformed values) according to EBV status (EBV− and EBV+) (A) and epidemiological variant (endemic BL and sporadic BL) (B) of 117 pediatric BL cases. Red circle highlights high SOX11 expression in 3 BLs from endemic areas. Wilcoxon text was performed to test differences between groups. (C) Frequency of patients who are SOX11+ and SOX11− (by IHC) in an independent series of pediatric and adult sBLs (n = 189), according to EBV status. The Cochran-Mantel-Haenszel test was performed to test differences between the frequency in EBV− and in EBV+, while adjusting for cohort and group.

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