MRD dynamics and rates. (A) MRD levels of patients who still had detectable MRD in PB by FCM at RE. In 7 of 10 patients (green lines), undetectable MRD is achieved with ongoing maintenance; in 1 patient (red line and star), a transformation to Hodgkin lymphoma occurred while on treatment, and in 2 patients (red lines), MRD was still detected after 8 cycles of maintenance. (B) Undetectable MRD rates are shown for all patients at the RE. In addition, the best uMRD rates for all patients and those with prior exposure to BTK inhibitors and/or venetoclax are shown. (C) Time to achievement of undetectable MRD by FCM in PB. The median time to achievement of the uMRD is 5.4 months. M1-8, maintenance staging 1-8; Pts, patients; ven, venetoclax.