FigureĀ 5.
Lower expression of Kitl and Igf1 in MSCs correlates with increased expression of differentiation-inactive HSCs and decreased expression of lymphoid signatures in HSCs. (A) Correlation between Igf1 expression in Adipo-MSC-1 and differentiation-inactive HSC signature (left), and Kitl expression in Adipo-MSC-1 and differentiation-inactive HSC signature, in individual MA mice (right). Each dot represents one mouse. (B) Correlation between Igf1 expression in Adipo-MSC-1 and lymphoid progenitor signatures and genes in HSCs in individual MA mice (top). Correlation between Kitl expression in Adipo-MSC-1 and lymphoid progenitor signatures and genes in HSCs in individual MA mice (bottom). Each dot represents 1 mouse. Pearson correlation, nominal P values.

Lower expression of Kitl and Igf1 in MSCs correlates with increased expression of differentiation-inactive HSCs and decreased expression of lymphoid signatures in HSCs. (A) Correlation between Igf1 expression in Adipo-MSC-1 and differentiation-inactive HSC signature (left), and Kitl expression in Adipo-MSC-1 and differentiation-inactive HSC signature, in individual MA mice (right). Each dot represents one mouse. (B) Correlation between Igf1 expression in Adipo-MSC-1 and lymphoid progenitor signatures and genes in HSCs in individual MA mice (top). Correlation between Kitl expression in Adipo-MSC-1 and lymphoid progenitor signatures and genes in HSCs in individual MA mice (bottom). Each dot represents 1 mouse. Pearson correlation, nominal P values.

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