Outcomes in patients with and without mutations in MDS-associated genes. (A) Kaplan-Meier curve of OS in all patients with NPM1 mutant, by the presence of mutations in MDS-associated genes. (B) CIR in all patients with NPM1 mutant, by the presence of mutations in MDS-associated genes. (C) Kaplan-Meier curve of OS in ELN22 favorable-risk patients with NPM1 mutant, by the presence of mutations in MDS-associated genes. (D) CIR in ELN22 favorable-risk patients with NPM1 mutant, by the presence of mutations in MDS-associated genes.