PK/PD evaluation of CG001 in rats and cynomolgus monkeys. (A-B) PK was evaluated by measuring the serum CG001 concentration in rats. n = 12 per group. (C-D) PK/PD correlation of CG001 in monkeys. Complement activity was measured by the Wieslab complement system AP kit. n = 6 per group. Values represent mean ± SD.