Clonotype assignment across patients. (A) UMAP representing the overall of 5 patients’ BCR profiling, in which clonal and polyclonal cells are represented by red and blue dots, respectively. (B) Violin plot showing the normalized expression levels of representative selected marker genes in clonal and polyclonal cells of each patient. (C) UMAP color coded for clonal and polyclonal cells (red and blue dots, respectively) of P2, P3 and P5 patients. (D-E) Dominant clonotypes of P1 and P4 patients represented by UMAP. Dominant clonotypes are represented by red and green dots and the polyclonal cells by blue dots. (F-G) Violin plots showing the expression levels of PCs representative selected marker genes across the clonotypes of P1 and P4 patients, respectively.