Underlying mutations and gene deregulation in patients with AML defined by the phenotypic stage of blast arrest. (A) Percentage of patients with HPC- and maturing-like AML carrying somatic mutations in each gene. (B) Top 10 more frequent mutated genes among HPC- and maturing-like AML cohorts. (C) Volcano plot showing differentially expressed genes between HPC- vs maturing-like AML subtypes. (D) Violin plots showing upregulated genes in patients with HPC-like AML. Outliers were removed for improved visualization. (E) Violin plots showing upregulated genes in patients with maturing-like AML. Outliers were removed for improved visualization.