Trauma patient plasma collected out to 7 days after injury was analyzed by standard clinical assays and MS proteomics. (A) Patient baseline characteristics and demographics showing median (range) or proportion of specified variable. (B) Number of samples collected per time point. (C) Scatterplot of patients specified by tissue injury (NISS, x-axis) or shock (base excess [BE], y-axis) upon hospital arrival into shock-trauma (ST) groups of LSLT, LSHT, HSLT, or HSHT. Diamonds indicate death. BMI, body mass index; BPM, beats per minute; ICU, intensive care unit; SBP, systolic blood pressure; TBI, traumatic brain injury.