Fibrinogen supplementation increases MS fibrinogen levels but does not increase Clauss activity. (A) Percent change from ED to 6 hours after injury of (A) Clauss activity after cryoprecipitate transfusion, (B) MS fibrinogen levels after cryoprecipitate transfusion, (C) Clauss activity after platelet transfusion, and (D) MS fibrinogen levels after platelet transfusion.