Effect of ITP vs control plasma treatment on the expression of apoptosis genes in MEG-01 cells. Apoptosis genes were significantly upregulated in ITP plasma–treated compared with the control plasma–treated and untreated cell conditions. Relative mRNA levels of each sample normalized to control condition (pan-caspase inhibitor [CI]) are shown as mean ± SD. Statistical analyses were performed using 1-way ANOVA followed by multiple comparisons tests to compare the mean ranks between the groups.