Effects of Rap on apoptosis genes in MEG-01 cells.CLU, CASP-3, TP53, and BAX were significantly downregulated after ITP plasma and Rap treatment compared with in the other 2 control conditions. Relative mRNA levels of each sample normalized to control condition (Rap) are shown as mean ± SD. Statistical analyses were performed using 1-way ANOVA followed by multiple comparisons tests to compare the mean ranks between the groups.