Effects of siRNA transfections targeting CLU and GRP78 in MEG-01 cells. mRNA levels of CLU, GRP78, and BAX determined by qRT-PCR in MEG-01 cells treated with plasma from patients with ITP compared with plasma from healthy controls, and transfected with siRNA targeting (A) CLU or (B) GRP78 are shown. Statistical analyses were performed using 1-way ANOVA followed by multiple comparisons tests to compare the mean ranks between groups. Expression levels are shown as mean; error bars show SDs and P values.