Figure 7.
Effect of the blocking anti-FXI antibody, 3G3, on sVE-cadherin levels after infusion of heat-inactivated S aureus into baboons. Time course change of sVE-cadherin levels. Data are mean ± standard deviation (SD) (n = 3). Same time points are compared between baboons challenged with 3 × 1010 colony forming units of S aureus per kg, and S aureus plus the blocking anti-FXI antibody, 3G3 (SA + 3G3) using 2-tailed student t test; ∗P < .05.