Clinical and cytogenetic markers associated with response to venetoclax. (A) Stratification of patients based on the presence of the t(11;14) translocation involving CCND1. (B) Multivariate analysis of clinical and cytogenetic markers for PFS. (C) Stratification of patients with t(11;14) based on the presence of 1q gain (n = 48). ∗, P<0.05; ∗∗, P<0.01; AIC, Akaike Information Criterion; ISS, International Staging System.