Paired FLT3-ITD and NPM1^mut MRD status. (A) MRD kinetics of FLT3-ITD and NPM1^mut and corresponding frequencies of MRD^neg status of respective pts during therapy and early FU. (B) CIR and (C) OS according to FLT3-ITD MRD and NPM1^mut MRD status after Cy2 (1 pt with FLT3-ITD MRD^pos/NPM1^mut MRD^neg was excluded). Dx, diagnosis; pts, patients.