Summary of initial therapy, retreatment, and its outcome in the CLL13/GAIA trial. The type of frontline therapy (“study treatment”) and corresponding salvage therapy (“second-line treatment”) (color coded) with numbers of patients is shown on the left. The outcome of second-line therapy by treatment type (time to next treatment from start of second-line therapy) is shown on the right. Data modified with permission from Fürstenau et al.²⁷