Causes and consequences of splenectomy in ALPS-FAS. Outcomes for all 66 patients undergoing splenectomy are shown. Each blue bar represents the timeline of events in 1 patient's lifetime, and all the bars are stacked from the oldest patient in the cohort at the bottom to the youngest at the top. All 6 deaths due to sepsis were in patients who underwent splenectomy at a younger age (<10 years).