Figure 5.
Transcriptomic analysis of arterial thrombus from different vascular beds. RNA was extracted and the expression of genes involved in inflammation and fibrosis was determined in arterial thrombi extracted from patients with infrarenal (n = 6) at the time of surgical repair or from the brain after acute thrombotic stroke (n = 5) at the time of catheter thrombectomy. (A) Heat map and (B) Volcano plot and Gene Ontology analysis for biological pathways in the thrombus. (C) Cellular and biochemical processes increased or decreased in aortic thrombus with respect to brain thrombus. FC, fold change.