Mean serum concentrations (mcg/mL) and semi-log (inset) over time (days) in part 1 (SAD). The 0.05 mg/kg cohort was not included due to only 1 participant demonstrating measurable serum levels. Note, concentrations reported as below the lower limit of quantification (LLOQ; LLOQ = 1.17 μg/mL) were set to 0 for the calculation of summary statistics.