Most common treatment-emergent AEs. (A) All-grade treatment-emergent AEs occurring in ≥15% of patients. (B) Most common grade ≥3 treatment-emergent AEs. Value reported in cumulative prevalence rate at 42.5-month follow-up. Dark fill indicates percent of patients with an AE at 29.6-month median follow-up; lighter fill indicates change in percent of patients with AE from 29.6 months to 42.5-month median follow-up. URTI, upper respiratory tract infection.