Ianalumab mechanism of action and current autoreactive B-cell targets for the treatment of immune thrombocytopenia

Abbreviations: APRIL, a proliferation-inducing ligand; BAFF, B-cell activating factor; BAFF-R, B-cell activating factor receptor; BCMA, B-cell maturation antigen; BCR, B-cell receptor; BTK, Bruton tyrosine kinase; SYK, spleen tyrosine kinase; TACI, transmembrane activator and calcium-modulator and cyclophilin ligand (CAML) interactor.