Summary plots of the repeatability of TRUST MRI method in SCD. (A) A scatterplot of relaxation rates (R₂) from sequential TRUST scans for each subject (n = 142) is shown. Spearman correlation analysis of the sequential R₂ measurements from TRUST demonstrates significant correlation (R = 0.940; P < .001). (B) A Bland-Altman plot portrays the mean R₂ of the sequential TRUST scans and the difference between scans for each participant. ICC analysis demonstrates excellent repeatability (ICC = 0.946) of the TRUST scan in persons with SCD. SD, standard deviation.