Component analysis of EASIX and m-EASIX scores over time by CRS and ICANS severity in pediatric and AYA patients treated with CD19-CAR T cells. Box plots representing the individual components of the EASIX and m-EASIX scores at days –5, 0, and +3 by severity of CRS (A-D) or ICANS (E-H). Asterisk (∗) indicates P < .05 from the univariate logistic regression between the component and the onset of severe CRS or ICANS. CR, complete response.