Genetic landscape of testicular follicular lymphoma. (A) Summary of sequencing and FISH findings in cases of T-FL. (B) Distribution of TNFRSF14 and IRF8 mutations at the protein level. BCR, B-cell receptor; JAK/STAT, Janus kinase/signal transducer and activator of transcription; MAPK, mitogen-activated protein kinase; NOTCH, notch signaling pathway; P13K/mTOR, phosphoinositide 3-kinase-mammalian target of rapamycin.