Treatment use line graph. Frequency of therapy receipt by year among patients treated in 2014 and thereafter in the rw setting. Percentages indicate person-LOTs in the given year, meaning that if a patient initiated 2L and 3L in 2015, both LOTs would be represented in 2015 as unique LOTs. If patients received BTKi and BCL2i in the same LOT, the patient is represented in both categories. If the patient received CIT in 1 LOT, the patient is represented only in “Chemotherapy and CD20”; this is also true of “PI3K and CD20.” HSCT: hematopoietic stem cell transplantation.