Phenotypes of K562 CML cells identified by single-cell RNA sequencing with and without drug treatment. (A) UMAP of K562 cells from all conditions. The genes in boxes indicate marker genes for each cluster. Genes are selected from a list of differentially expressed genes based on significant P value, fold change, and biological relevance. (B) UMAPs of K562 cells from selected drug conditions. Dots colored red (TRUE) represent K562 cells from the respective condition, and gray dots (FALSE) represent K562 cells from all other conditions. (C) Bar plot showing percentages of K562 cells in each cluster by experimental/drug condition.