Epigenetic-based stratification in pediatric T-ALL. In this study the authors performed array-based methylome analysis in pediatric T-ALL issued from 2 pediatric cohorts: the Nordic NOPHO AALL2008 (n = 192) and the Dutch DCOG ALL10/11 (n = 156). The authors identified 2 distinct epigenetic phenotypes, namely, CIMP low and high, and demonstrated the prognostic relevance of this CIMP classification, identifying both high-risk and low-risk groups of patients when combined with MRD status at the EOI. Created with BioRender.com.

Epigenetic-based stratification in pediatric T-ALL. In this study the authors performed array-based methylome analysis in pediatric T-ALL issued from 2 pediatric cohorts: the Nordic NOPHO AALL2008 (n = 192) and the Dutch DCOG ALL10/11 (n = 156). The authors identified 2 distinct epigenetic phenotypes, namely, CIMP low and high, and demonstrated the prognostic relevance of this CIMP classification, identifying both high-risk and low-risk groups of patients when combined with MRD status at the EOI. Created with BioRender.com.

Close Modal
This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal