Kinetics of clonal relapse and eradication in participants with post-HCT MRD. Each line on the plots depicts a single FLT3-ITD clone detected with the MRD assay, starting with randomization. In a limited number of cases, a sample was available at relapse, analyzed with conventional capillary electrophoresis PCR, and the length of the FLT3-ITD clone was identical to the clone detected in the MRD assay. These clones are depicted with red lines. The blue lines depict cases in which the relapse specimen was not available for analysis and so the length could not be confirmed. (A) Placebo arm, from randomization to 2 years of follow-up. (B) Placebo arm, depicting only the first 24 weeks of follow-up after randomization. (C) Gilteritinib arm, from randomization to 2 years of follow-up. (D) Gilteritinib arm, depicting only the first 24 weeks of follow-up after randomization.