Alteration of immune effector cell subsets after initiation of pomalidomide, ixazomib, dexamethasone. Peripheral blood samples taken at day 1 (before treatment), and day 15 (after 2 weeks of pomalidomide, ixazomib, and dexamethasone) were analyzed by flow cytometry to identify changes in the immune subsets associated with treatment. The CD69 expression on NK-T cells was increased (left plot), LAG3 expression was increased on helper T cells (center plot), and TIM3 expression decreased on T cells (right plot). gMFI, gated mean fluorescence intensity; Ixa-Pom, ixazomib, pomalidomide.