Figure 4.
Similarity of orthologous transcripts and proteins in human and mouse platelets. (A) Plot of transcript values [log2(tpm + 1); tpm normalized; means of 5 transcriptomes] comparing human and mouse platelets. (B) Plot of protein copy numbers (calibrated; means of 5 proteomes) comparing human and mouse platelets. Shown are results of regression analysis with indicated number of gene products. (C) Partial overlap (in black) of orthologous transcripts in human and mouse platelets per function class (C01-C23; RNA genes; pseudogenes). The relevant transcript level was set at 0.03. (D) Partial overlap (in black) of detected proteins in human and mouse platelets per function class. Not identified means absent in proteome but present in transcriptome. Plt, platelets.