Clearance of control and AMT-treated donor RBCs after transfusion. Transfused control and AMT-treated donor RBCs in circulation normalized to the mean number of control RBCs at 24 hours (A; N = 7) and over 35 days (B). After the initial clearance of 27.5% of the less deformable RBCs in the AMT-treated sample, the control and remaining AMT-treated RBCs are cleared with a half-life of 21.4 and 20.8 days, respectively.