Molecular interactions at the FVa-APC interface. Representative interactions at the interface between FVa (cyan sticks) and APC (magenta sticks), also shown in Figure 4 and detailed in Table 2. (A) Interactions between residues H379, V381, N382, and M385 of FVa with the autolysis loop of APC. (B) Interactions between residues D513, T579, and T626 of FVa with the 30-loop of APC. (C) Interactions between residue R510 of FVa with the 60-loop of APC. (D) Interactions between residues R400 and R501 of FVa with the 90-loop of APC. (E) Interactions between residues D660, E662, and E666 of the latch of FVa with the 70-loop of APC.