Summary of key immunophenotypic, cytogenetic, and molecular changes from baseline to LS. Illustration encompassing all 70 patients with LS including individual patient data. Each column represents an individual participant case. Each row represents a demographic-, treatment-, or disease-related characteristic; some characteristics further divided into rows at baseline (diagnosis or relapse before discovery of LS) and at the time of LS diagnosis. All characteristics are categorical and defined by the colors as described in the figure legend. Immunophenotypic data categorized as not reported/unknown if the flow report was unavailable or if the flow report did not comment on the specific antigen. AYA, adolescent young adult; cMPO, cytoplasmic myeloperoxidase; HSCT, hematopoietic stem cell transplant; LS, lineage switch.