Clonal interrelationships between MM and CHIP. Oncoplot representing the occurrence of mutations indicative of myeloid or lymphoid clonality in HSCs and PCs flow sorted from the BM of 8 CHIP-positive patients with MM. For each patient, the CHIP-defining mutated genes identified in peripheral WBCs are also reported, in the first column. The smaller orange square refers to a mutation at a VAF <2%. The abbreviation “n.a.” stands for not available information and regards the mutational status of MM driver genes, not sequenced in peripheral WBCs.