Figure 2.
rs3916765 is an eQTL for HLA class 2 genes in whole-blood. (A) rs3916765 genotype–specific expression of HLA-DQA2 and HLA-DOB in whole-blood from GTEx. (B) Associations between genotypes at rs3916765 and gene expressed in whole-blood in Leucegene. The effect size (x-axis) is given for the AML risk G-allele. P values (y-axis) were adjusted with the Benjamini-Hochberg (false discovery rate) procedure. The horizontal line corresponds to an adjusted P = .05. Red points correspond to HLA class 2 genes. (C) Genotype-specific whole-blood expression of HLA class 2 genes stratified by genotypes at rs3916765 in Leucegene participants. ∗nominal P < .05; ∗∗nominal P < .01; ∗∗∗ nominal P < .001. P_adj, adjusted P value.

rs3916765 is an eQTL for HLA class 2 genes in whole-blood. (A) rs3916765 genotype–specific expression of HLA-DQA2 and HLA-DOB in whole-blood from GTEx. (B) Associations between genotypes at rs3916765 and gene expressed in whole-blood in Leucegene. The effect size (x-axis) is given for the AML risk G-allele. P values (y-axis) were adjusted with the Benjamini-Hochberg (false discovery rate) procedure. The horizontal line corresponds to an adjusted P = .05. Red points correspond to HLA class 2 genes. (C) Genotype-specific whole-blood expression of HLA class 2 genes stratified by genotypes at rs3916765 in Leucegene participants. ∗nominal P < .05; ∗∗nominal P < .01; ∗∗∗ nominal P < .001. P_adj, adjusted P value.

This Feature Is Available To Subscribers Only

or Create an Account

Close Modal
Close Modal