Comparative mutational landscape. (A) Mutational profile of control (blue; n = 50) and mBEP (red; n = 17) breast cancer cohorts. Each column represents an individual patient. Blue rectangles indicate the presence of mutations in specific genes. The frequency of each mutation is represented by horizontal bars (right), according to the patient cohorts. (B) Lollipop plot of 18 BAX variants (NM_138761.3) detected in 5 patients with breast cancer after venetoclax treatment (mBEP cohort; top), and the previously described 28 BAX variants in 13 patients with CLL cohort (bottom). Created with ProteinPaint. Zhou X. (2016).