Kaplan-Meier analysis of the observed time to T_loss by day 28 response category in patients with B-ALL and month 3 response category in patients with DLBCL. (A) Among patients with B-ALL, the HR for response vs no response (NR) was 1.79 (95% confidence interval [CI], 0.64-4.99). (B) Among patients with DLBCL, the HR for response vs NR was 4.19 (95% CI, 2.19-8.02). For these analyses, the first observed T_loss for a patient was considered as an event, while patients without an observed T_loss were censored at T_last. T_loss was determined as the first available time point after C_max when transgene levels dropped below 50 copies per μg of DNA and was considered as an event, while patients with no observed T_loss were censored at the last observation (T_last). PD, progressive disease; PR, partial response; SD, stable disease; UNK, unknown.