Figure 5.
CD19+ MRD and transgene persistence in patients with B-ALL. Time to loss of transgene for an ongoing response >6 months or CD19 status color coded by day 28 NGS MRD status. Horizontal bars represent median values, and circles represent values outside of 1.5 × interquartile range. Lower and upper whiskers extend to the most extreme points within 1.5 × interquartile range of quartile 1 and quartile 3, respectively. Tloss was determined as the first available time point after Cmax when transgene levels dropped <50 copies per μg of DNA.

CD19+ MRD and transgene persistence in patients with B-ALL. Time to loss of transgene for an ongoing response >6 months or CD19 status color coded by day 28 NGS MRD status. Horizontal bars represent median values, and circles represent values outside of 1.5 × interquartile range. Lower and upper whiskers extend to the most extreme points within 1.5 × interquartile range of quartile 1 and quartile 3, respectively. Tloss was determined as the first available time point after Cmax when transgene levels dropped <50 copies per μg of DNA.

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