Distribution of SRSF2 mutations in MDS and AML. (A) Proportion of SRSF2 mutations in the MDS cohort (n = 698) separated by WHO entities. wt, wildtype (gray); mut, mutated (red); LB, low blasts; IB, increased blasts. (B) Proportion of SRSF2 mutations in the AML cohort (n = 744) separated by WHO entities. wt, wildtype (gray); mut, mutated (red); diff, defined by differentiation.