Figure 5.
Quantile-quantile plot of observed vs expected P values from the genome-wide association analysis for positive controls, negative controls, and hypothesis-based PA pathway genes and VTE incidence. Expected vs observed –log10 of P values. Data points showing negative control genes (gray) and PA pathway genes (red) overlap. The minimum P value for F5 (rs6025, FV Leiden, P < 1.00E-300) is not shown in the plot.

Quantile-quantile plot of observed vs expected P values from the genome-wide association analysis for positive controls, negative controls, and hypothesis-based PA pathway genes and VTE incidence. Expected vs observed –log10 of P values. Data points showing negative control genes (gray) and PA pathway genes (red) overlap. The minimum P value for F5 (rs6025, FV Leiden, P < 1.00E-300) is not shown in the plot.

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