Analysis of skeletal muscle microvasculature indices and determinants among sex for CONs, carriers of SCT, and patients with SCD. (Ai) Representative micrograph of skeletal muscle cryosections stained for CD31 (endothelial cells), NG2, and αSMA (both for pericytes). Focus on a single skeletal muscle capillary with split channels. Scalebar: 10 μm. (Aii) Large view of muscle cryosections for each condition. Scale bar, 100 μm. (B-G). Comparison of skeletal muscle microvasculature indexes and determinants between genotype and sex (white bar, females; gray bar, males). The effects of genotype ∗ sex and sex were obtained with 2-way ANOVA analysis. Post hoc analysis: ^a,b,c,dconditions not sharing the same letter were significantly different (P < .05). NG2, neural-glial antigen 2.