The PDA score identifies patients with (any grade) ICANS prior to clinical symptoms. (A) Receiver operating characteristic curve of the prediction of any grade ICANS based on the PDA score. (B) Performance metrics of the PDA score to predict any grade ICANS. (C) Cumulative incidence of any grade ICANS and PDA scores ≥3 and ≥4. (D) Number of hours the PDA score can predict ICANS onset prior to clinical symptoms.