Figure 3.
Comparison of nascent reticulocytes proteome (BMRetic) with Gautier et al25 data of mature reticulocytes (CircRetic) and purified circulating erythrocytes (CircEryth). (A) Mean number of quantified proteins in each population. Statistics: 1-way analysis of variance; ∗∗∗∗P < 0001. (B) Venn diagram of quantified proteins in each population (proteins quantified in at least 1 sample). (C) Pearson correlations of log2(protein copy numbers per cell) between each sample. (D) Mean quantity (in picograms per cell) of globins and other proteins in each population. (E) Principal component analysis of log2(protein copy numbers per cell) of every sample (proteins with at least 70% of valid values in at least 1 condition were selected). BM, bone marrow.