Figure 5.
Mean protein copy numbers in nascent reticulocytes (BM Retics), mature reticulocytes (CircRetics), and circulating erythrocytes (CircEryth) (logarithmic scale). Only means quantified with at least 3 values are shown. (A) Cytoskeletal proteins. (B) Membrane proteins. (C) Cell adhesion proteins. (D-G) Top 15 in nascent reticulocytes of protein kinases (D) and protein phosphatases (E) and examples of proteins associated to the GOCC “proteasome complex” (F) and GOBP “proteasome-mediated ubiquitin-dependent protein catabolic process” (G). (H) Examples of proteins associated to O2 and CO2 transport, and (I) oxidative stress regulation. BM, bone marrow.