Mean protein copy numbers in nascent reticulocytes (BM Retics), mature reticulocytes (CircRetics), and circulating erythrocytes (CircEryth) (logarithmic scale). Only means quantified with at least 3 values are shown. (A) Cytoskeletal proteins. (B) Membrane proteins. (C) Cell adhesion proteins. (D-G) Top 15 in nascent reticulocytes of protein kinases (D) and protein phosphatases (E) and examples of proteins associated to the GOCC “proteasome complex” (F) and GOBP “proteasome-mediated ubiquitin-dependent protein catabolic process” (G). (H) Examples of proteins associated to O2 and CO2 transport, and (I) oxidative stress regulation. BM, bone marrow.
Figure 5.

Mean protein copy numbers in nascent reticulocytes (BM Retics), mature reticulocytes (CircRetics), and circulating erythrocytes (CircEryth) (logarithmic scale). Only means quantified with at least 3 values are shown. (A) Cytoskeletal proteins. (B) Membrane proteins. (C) Cell adhesion proteins. (D-G) Top 15 in nascent reticulocytes of protein kinases (D) and protein phosphatases (E) and examples of proteins associated to the GOCC “proteasome complex” (F) and GOBP “proteasome-mediated ubiquitin-dependent protein catabolic process” (G). (H) Examples of proteins associated to O2 and CO2 transport, and (I) oxidative stress regulation. BM, bone marrow.

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